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Horns disease
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Subni at her table in The Shining Pearl.
The horns disease is a non-contagious illness that causes the afflicted's bones to grow horn-like protrusions randomly. The disease seems to be painless but can still be a burden for obvious reasons. The only known person with it is Subni.
The condition is named after The Horns, a city built into large and tall horn-like mountains. While it is said that the disease originates from there, it is unknown if it actually relates to it at all.